Shared heritability and functional enrichment across six solid cancers

Uppsala universitet, Ortopedi ; Harvard TH Chan Sch Publ Hlth, Program Genet Epidemiol & Stat Genet, 677 Huntington Ave, Boston, MA 02115 USA;Karolinska Inst, Inst Environm Med, Unit Cardiovasc Epidemiol, Nobels Vagen 13, S-17177 Stockholm, Sweden ; Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, 677 Huntington Ave, Boston, MA 02115 USA;Broad Inst MIT & Harvard, Program Med & Populat Genet, 75 Ames St, Cambridge, MA 02142 USA ; Case Western Reserve Univ, Dept Populat & Quantitat Hlth Sci, 10900 Eucid Ave, Cleveland, OH 44106 USA;Univ Hosp, Seidman Canc Ctr, Cleveland, OH 44106 USA ; H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, 12902 Magnolia Dr MRC CANCONT, Tampa, FL 33612 USA;H Lee Moffitt Canc Ctr & Res Inst, Dept Gastrointestinal Oncol, 12902 Magnolia Dr MRC CANCONT, Tampa, FL 33612 USA ; Univ Cambridge, Dept Oncol, Ctr Canc Genet Epidemiol, 2 Worts Causeway, Cambridge CB1 8RN, England ; Geisel Sch Med Dartmouth, Dept Biomed Data Sci, 1 Med Ctr Dr, Dartmouth, NS, Lebanon ; Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, 2 Worts Causeway, Cambridge CB1 8RN, England;Cyprus Inst Neurol & Genet, Dept Elect Microscopy Mol Pathol, CY-1683 Nicosia, Cyprus ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;Int Agcy Res Canc, Sect Genet, 150 Cours Albert Thomas, F-69008 Lyon, France ; UCL, Div Psychiat, Maple House,149 Tottenham Court Rd, London W1T 7NF, England;UCL, UCL Genet Inst, Gower St, London WC1E 6BT, England ; Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, 2 Worts Causeway, Cambridge CB1 8RN, England ; Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 48109 USA ; Univ Virginia, Publ Hlth Sci, POB 800717, Charlottesville, VI 80071 USA;Univ Virginia, Ctr Publ Hlth Genom, POB 800717, Charlottesville, VI 80071 USA ; Amer Canc Soc, Epidemiol Res Program, 250 Williams St NW, Atlanta, GA 30303 USA ; Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, 1100 Fairview Ave N, Seattle, WA 98109 USA ; NCI, Div Canc Epidemiol & Genet, 9609 Med Ctr Dr, Rockville, MD 20850 USA ; Vanderbilt Univ, Div Epidemiol, Dept Thorac Surg, Med Ctr, 609 Oxford House, Nashville, TN 37232 USA ; Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Fred ALitwin Ctr Canc Genet, 600 Univ Ave, Toronto, ON M5G 1X5, Canada;Univ Toronto, Dept Mol Genet, 1 Kings Coll Circle, Toronto, ON M5S 1A8, Canada ; Univ Calif Irvine, Genet Epidemiol Res Inst, Dept Epidemiol, 224 Irvine Hall, Irvine, CA 92617 USA ; NNAlexandrov Res Inst Oncol & Med Radiol, Settlement Lesnoy 2, Minsk 223040, BELARUS ; Univ Kentucky, Markey Canc Ctr, 800 Rose St,Cc445, Lexington, KY 40508 USA ; Queens Univ, Dept Publ Hlth Sci, 10 Stuart St, Kingston, ON K7L 3N6, Canada;Queens Univ, Canc Res Inst, 10 Stuart St, Kingston, ON K7L 3N6, Canada ; Univ Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, 1155 Pressler St, Houston, TX 77030 USA ; Rutgers Canc Inst New Jersey, Canc Prevent & Control Program, 195 Little Albany St,Room 5568, New Brunswick, NJ 08903 USA ; Landspitali Univ Hosp, Dept Pathol, IS-101 Reykjavik, Iceland;Univ Iceland, Fac Med, BMC Biomed Ctr, Vatnsmyrarvegi 16, IS-101 Reykjavik, Iceland ; Australian Prostate Canc Res Ctr Qld, Translat Res Inst, 37 Kent St, Woolloongabba, Qld 4102, Australia;Queensland Univ Technol, Inst Hlth & Biomed Innovat, 60 Musk Ave, Kelvin Grove, Qld 4059, Australia;Queensland Univ Technol, Sch Biomed Sci, 60 Musk Ave, Kelvin Grove, Qld 4059, Australia ; Friedrich Alexander Univ Erlangen Nuremberg, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen Nuremberg, Dept Gynecol & Obstet, Univ Str 21-23, D-91054 Erlangen, Germany ; Spanish Natl Canc Res Ctr CNIO, Human Canc Genet Programme, Calle Melchor Fernandez Almagro 3, Madrid 28029, Spain;Biomed Network Rare Dis CIBERER, AvMonforte Lemos,3-5Pabellon 11Planta 0, Madrid 28029, Spain ; Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, 2 Worts Causeway, Cambridge CB1 8RN, England;Inst Canc Res, Div Genet & Epidemiol, 15 Cotswold Rd, Sutton SM2 5NG, Surrey, England ; Duke Univ, Dept Obstet & Gynecol, Med Ctr, 25171 Morris Bldg, Durham, NC 27710 USA ; Univ Med Ctr Goettingen, Dept Genet Epidemiol, Humboldtallee 32, D-37073 Gottingen, Germany ; Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, 1100 Fairview Ave N, Seattle, WA 98109 USA;Univ Washington, Sch Publ Hlth, 1959 NE Pacific St,Hlth Sci Bldg,F-350, Seattle, WA 98195 USA ; Univ Helsinki, Helsinki Univ Hosp, Dept Oncol, Haartmaninkatu 4, FIN-00290 Helsinki, Finland;Orebro Univ Hosp, Dept Oncol, S-70185 Orebro, Sweden ; Fdn Policlin Univ AGemelli IRCCS, I-00168 Rome, Italy;Univ Cattolica Sacro Cuore, I-00168 Rome, Italy ; NNAlexandrov Res Inst Oncol & Med Radiol, Settlement Lesnoy 2, Minsk 223040, BELARUS;Hannover Med Sch, Dept Radiat Oncol, Carl Neuberg Str 1, D-30625 Hannover, Germany;Hannover Med Sch, Gynaecol Res Unit, Carl Neuberg Str 1, D-30625 Hannover, Germany ; Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Copenhagen Gen Populat Study, Herlev Ringvej 75, DK-75 Herlev, Denmark;Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Clin Biochem, Herlev Ringvej 75, DK-75 Herlev, Denmark;Univ Copenhagen, Fac Hlth & Med Sci, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark ; DrMargarete Fischer Bosch Inst Clin Pharmacol, Auerbachstr112, D-70376 Stuttgart, Germany;Univ Tubingen, Geschwister Scholl Pl, D-72074 Tubingen, Germany;German Canc Res Ctr, German Canc Consortium DKTK, Neuenheimer Feld 280, D-69120 Heidelberg, Germany ; German Canc Res Ctr, German Canc Consortium DKTK, Neuenheimer Feld 280, D-69120 Heidelberg, Germany;German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Neuenheimer Feld 280, D-69120 Heidelberg, Germany;German Canc Res Ctr, Div Prevent Oncol, Neuenheimer Feld 280, D-69120 Heidelberg, Germany;Natl Ctr Tumor Dis NCT, Neuenheimer Feld 280, D-69120 Heidelberg, Germany ; Univ Cambridge, Canc Res UK Cambridge Inst, Li Ka Shing Ctr, Robinson Way, Cambridge CB2 0RE, England ; Inst Canc Res, Div Genet & Epidemiol, 15 Cotswold Rd, Sutton SM2 5NG, Surrey, England ; CIBERONC, Catalan Inst Oncol, IDIBGI Inst Invest Biomed Girona, Genet Counseling Unit,Hereditary Canc Program, AvFranca S-N, Girona 17007, Spain ; Lund Univ, Clin Sci, Box 117, S-22100 Lund, Sweden;Dept Genet & Pathol, Div Lab Med, S-22185 Lund, Sweden ; Univ Melbourne, Victorian Comprehens Canc Ctr, Ctr Canc Res, Parkville, Vic 3010, Australia;Univ Melbourne, Dept Clin Pathol, Colorectal Oncogen Grp, Parkville, Vic 3010, Australia;Royal Melbourne Hosp, Genom Med & Family Canc Clin, Parkville, Vic 3010, Australia ; Heidelberg Univ, Dept Obstet & Gynecol, Neuenheimer Feld 440, D-69120 Heidelberg, Germany;German Canc Res Ctr, Mol Epidemiol Grp, C080,Neuenheimer Feld 280, D-69120 Heidelberg, Germany ; Univ Helsinki, Dept Pathol, Biomed Helsinki 4th Floor,Haartmaninkatu 8, Helsinki 00029, Finland;Helsinki Univ Hosp, Biomed Helsinki 4th Floor,Haartmaninkatu 8, Helsinki 00029, Finland ; Hosp Clin San Carlos, Inst Invest Sanitaria San Carlos IdISSC, Med Oncol Dept, Ctr Invest Biomed Red Canc CIBERONC, Calle Prof Martin Lagos, Madrid 28040, Spain ; Univ Pisa, Dept Lab Med, Sect Genet Oncol, Via Roma 67, I-56126 Pisa, Italy;Univ Hosp Pisa, Via Roma 67, I-56126 Pisa, Italy ; Peter MacCallum Canc Ctr, 305 Grattan St, Melbourne, Vic 3000, Australia;Univ Melbourne, Sir Peter MacCallum Dept Oncol, 305 Grattan St, Melbourne, Vic 3000, Australia ; Sorbonne Univ, Tenon Hosp, GRC N 5 ONCOTYPE URO, F-75020 Paris, France;Tenon Hosp, CeRePP, F-75020 Paris, France ; Univ Utah, Dept Med, Div Genet Epidemiol, Sch Med, Salt Lake City, UT 84112 USA;George EWahlen Dept Vet Affairs Med Ctr, Salt Lake City, UT 84112 USA ; German Canc Res Ctr, Div Canc Epidemiol, Neuenheimer Feld 280, D-69120 Heidelberg, Germany;Univ Pisa, Dept Biol, I-56126 Pisa, Italy ; Barretos Canc Hosp, Mol Oncol Res Ctr, Rua Antenor Duarte Villela 1331, BR-784400 Barretos, SP, Brazil;Barretos Canc Hosp, Head & Neck Surg Dept, Pio 12,1331 Antenor Duarte Villela St, BR-14784400 Barretos, SP, Brazil ; Massachusetts Gen Hosp, Div Gastroenterol, 55 Fruit St, Boston, MA 02114 USA;Harvard Med Sch, Brigham & Womens Hosp, Channing Div Network Med, Dept Med, 181 Longwood Ave, Boston, MA 02115 USA ; German Canc Res Ctr, Div Canc Epidemiol, Neuenheimer Feld 280, D-69120 Heidelberg, Germany;Univ Med Ctr Hamburg Eppendorf, UCCH, Canc Epidemiol Grp, Martinistr 52, D-20246 Hamburg, Germany ; Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Program Epidemiol, 1100 Fairview Ave N, Seattle, WA 98109 USA ; Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, 677 Huntington Ave, Boston, MA 02115 USA ; Univ Ghent, Ctr Med Genet, De Pintelaan 185, B-9000 Ghent, Belgium ; Katholieke Univ Leuven, Dept Cellular & Mol Med, Mol Endocrinol Lab, B-3000 Leuven, Belgium ; Erasmus MC, Dept Clin Genet, Wytemaweg 80, NL-3015 CN Rotterdam, Netherlands ; Univ Puerto Rico Med Sci Campus, San Juan, PR 00936 USA;Comprehens Canc Ctr, San Juan, PR 00936 USA ; Mayo Clin, Dept Lab Med & Pathol, 200 First StSW, Rochester, MN 55905 USA ; Univ Sheffield, Sheffield Inst Nucle Acids SInFoNiA, Dept Oncol & Metab, Western Bank, Sheffield S10 2TN, S Yorkshire, England ; Pomeranian Med Univ, Dept Genet & Pathol, Int Hereditary Canc Ctr, ulUnii Lubelskiej 1, PL-71252 Szczecin, Poland ; Karolinska Inst, Karolinska Univ Hosp, Dept Med Epidemiol & Biostat, S-17176 Stockholm, Sweden ; Fox Chase Canc Ctr, Dept Clin Genet, 333 Cottman Ave, Philadelphia, PA 19111 USA ; Univ Sydney, Westmead Inst Med Res, Ctr Canc Res, 176 Hawkesbury Rd, Sydney, NSW 2145, Australia;Westmead Hosp, Dept Gynaecol Oncol, Hawkesbury Rd & Darcy Rd, Sydney, NSW 2145, Australia ; Leiden Univ Med Ctr, Dept Pathol, Albinusdreef 2, NL-2333 ZA Leiden, Netherlands;Leiden Univ Med Ctr, Dept Human Genet, Albinusdreef 2, NL-2333 ZA Leiden, Netherlands ; Univ Hosp Vall dHebron, Vall dHebron Inst Oncol VHIO, Clin & Mol Genet Area, Oncogenet Grp, Passeig Vall dHebron 119-129, Barcelona 08035, Spain ; Complejo Hosp Univ Santiago, SERGAS, Inst Invest Sanitaria Santiago de Compostela IDIS, Genom Med Grp,Galician Fdn Genom Med, Travesia Choupana S-N, Santiago De Compostela 15706, Spain;Univ Calif San Diego, Moores Canc Ctr, 3855 Hlth Sci Dr, La Jolla, CA 92037 USA ; Univ Bristol, Sch Social & Community Med, Bristol BS8 1TH, Avon, England ; ICO IDIBELL, Canc Epidemiol Res Program, Unit Nutr & Canc, AvGran Via 199-203, Barcelona 08908, Spain ; Univ Westminster, Fac Sci & Technol, Dept Biomed Sci, 309 Regent St, London W1B 2HW, England ; Univ Southampton, Canc Sci Acad Unit, Fac Med, Tremona Rd, Southampton SO16 6YD, Hants, England ; Univ Southern Calif, Keck Sch Med, Dept Med, Los Angeles, CA 90033 USA ; Vanderbilt Univ, Med Ctr, Dept Obstet & Gynecol, Vanderbilt Epidemiol Ctr,Vanderbilt Genet Inst, 2525 West End Ave,Suite 600, Nashville, TN 37203 USA ; Lund Univ, Dept Canc Epidemiol, Clin Sci, Barngatan 4, S-22242 Lund, Sweden ; Univ Manchester, Cent Manchester Univ Hosp NHS Fdn Trust, Manchester Ctr Genom Med, Div Evolut & Genom Sci,St Marys Hosp, Oxford Rd, Manchester M13 9WL, Lancs, England ; Friedrich Alexander Univ Erlangen Nuremberg, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen Nuremberg, Dept Gynecol & Obstet, Univ Str 21-23, D-91054 Erlangen, Germany;Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Div Hematol & Oncol, 10833 Le Conte Ave, Los Angeles, CA 90095 USA ; Univ Pittsburgh, UPMC Hillman Canc Ctr, Dept Otolaryngol, Canc Pavil,Suite 500,5150 Ctr Ave, Pittsburgh, PA 15232 USA ; Univ Liverpool, Mol & Clin Canc Med, Roy Castle Lung Canc Res Programme, Inst Translat Med, Wiliam Duncan Bldg,6 West Derby St, Liverpool L69 3BX, Merseyside, England ; Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, 8700 Beverly Blvd, Los Angeles, CA 90048 USA;Univ Southern Calif, Keck Sch Med, 1450 Biggy St, Los Angeles, CA 90033 USA ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;Inst Canc Res, Breast Canc Now Toby Robins Res Ctr, 123 Old Brompton Rd, London SW7 3RP, England ; German Canc Res Ctr, Div Canc Epidemiol, Neuenheimer Feld 280, D-69120 Heidelberg, Germany ; Natl Ctr Sci Res Demokritos, Mol Diagnost Lab, INRASTES, Neapoleos 10, Athens 15310, Greece ; Int Agcy Res Canc, Sect Infect, 150 Cours Albert Thomas, F-69008 Lyon, France ; Chaim Sheba Med Ctr, Susanne Levy Gertner Oncogenet Unit, Emek HaEla St 1, IL-52621 Ramat Gan, Israel;Tel Aviv Univ, Sackler Fac Med, Haim Levanon 30, IL-69978 Ramat Aviv, Israel ; Mt Sinai Hosp, Dept Surg, 600 Univ Ave, Toronto, ON M5G 1X5, Canada;Samuel Lunenfeld Res Inst, 600 Univ Ave, Toronto, ON M5G 1X5, Canada;Univ Hlth Network Toronto Gen Hosp, 200 Elizabeth St, Toronto, ON M5G 2C4, Canada ; Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Div Canc Prevent & Control Res, Sch Med, 650 Charles Young Dr South, Los Angeles, CA 90095 USA;Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Div Canc Prevent & Control Res, Sch Publ Hlth, 650 Charles Young Dr South, Los Angeles, CA 90095 USA ; Dana Farber Canc Inst, Canc Risk & Prevent Clin, 450 Brookline Ave, Boston, MA 02215 USA ; Univ Southern Calif, Keck Sch Med, Dept Prevent Med, 1975 Zonal Ave, Los Angeles, CA 90033 USA;Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Ctr Canc Prevent & Translat Genom, Spielberg Bldg,8725 Alden Dr, Los Angeles, CA 90048 USA;Cedars Sinai Med Ctr, Dept Biomed Sci, Spielberg Bldg,8725 Alden Dr, Los Angeles, CA 90048 USA ; Canc Council Victoria, Canc Epidemiol & Intelligence Div, 615 St Kilda Rd, Melbourne, Vic 3004, Australia;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Level 1,723 Swanston St, Melbourne, Vic 3010, Australia;Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic, Australia ; Univ Kansas, Dept Pathol & Lab Med, Med Ctr, 3901 Rainbow Blvd, Kansas City, KS 66160 USA ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;McGill Univ, Dept Med, 1001 Decarie Blvd, Montreal, PQ H4A 3J1, Canada;McGill Univ, Royal Victoria Hosp, Div Clin Epidemiol, 1001 Decarie Blvd, Montreal, PQ H4A 3J1, Canada ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;Univ Utah, Huntsman Canc Inst, Dept Dermatol, Sch Med, 2000 Circle Hope, Salt Lake City, UT 84112 USA ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;Mayo Clin, Dept Hlth Sci Res, 200 First StSW, Rochester, MN 55905 USA ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Canc Prevent & Control, 8700 Beverly Blvd,Room 1S37, Los Angeles, CA 90048 USA;Cedars Sinai Med Ctr, Dept Biomed Sci, Commun & Populat Hlth Res Inst, 8700 Beverly Blvd,Room 1S37, Los Angeles, CA 90048 USA ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;Swedish Canc Inst, Div Publ Hlth Sci, 1221 Madison StSte 300, Seattle, WA 98109 USA ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;Umea Univ, Unit Clin Chem, Dept Med Biosci, 6M Van 2, S-90185 Umea, Sweden ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;NCI, Clin Genet Branch, DCEG, 9609 Med Ctr Dr, Bethesda, MD 20850 USA ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;Univ Paris Saclay, Univ Paris Sud, Ctr Res Epidemiol & Populat Hlth CESP, Canc & Environm Grp,INSERM, F-94805 Villejuif, France ; Karolinska Inst, Div Nutr Epidemiol, Dept Environm Med, Nobels Vag 13, S-17177 Stockholm, Sweden ; Karolinska Inst, Karolinska Univ Hosp, Dept Med Epidemiol & Biostat, S-17176 Stockholm, Sweden;Soder Sjukhuset, Dept Oncol, Sjukhusbacken 10, S-11883 Stockholm, Sweden ; German Canc Res Ctr, Mol Genet Breast Canc, Neuenheimer Feld 580, D-69120 Heidelberg, Germany ; Univ Oxford, John Radcliffe Hosp, Nuffield Dept Surg Sci, Fac Med Sci, Oxford OX1 2JD, England ; Princess Margaret Canc Ctr, Dept Surg Oncol, 610 Univ Ave, Toronto, ON M5G 2M9, Canada ; Tech Univ Dresden, Univ Hosp Dresden, Dept Internal Med 1, D-01307 Dresden, Germany ; German Canc Res Ctr, Div Canc Epidemiol, Neuenheimer Feld 280, D-69120 Heidelberg, Germany;Natl Inst Occupat Hlth STAMI, Gydas Vei 8, N-0033 Oslo, Norway ; DrHorst Schmidt Kliniken Wiesbaden, Dept Gynecol & Gynecol Oncol, Ludwig Erhard Str 100, D-65199 Wiesbaden, Germany;Knappschaft GmbH, Dept Gynecol & Gynecol Oncol, Kliniken Essen Mitte, EvangHuyssens Stiftung, Henricistr 92, D-45136 Essen, Germany ; Int Agcy Res Canc, Early Detect & Prevent Sect, 150 Cours Albert Thomas, F-69008 Lyon, France ; German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Neuenheimer Feld 280, D-69120 Heidelberg, Germany ; Danish Canc Soc Res Ctr, Dept Virus Lifestyle & Genes, Strandboulevarden 49, DK-2100 Copenhagen, Denmark;Univ Copenhagen, Herlev Hosp, Dept Pathol, Mol Unit, Herlev Ringvej 75, DK-75 Herlev, Denmark ; Seoul Natl Univ, Coll Med, Prevent Med, 1 Gwanak Ro, Seoul 151742, South Korea ; Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Level 1,723 Swanston St, Melbourne, Vic 3010, Australia ; Inst Canc Res, German Res Ctr Environm Hlth, Ingolstadter Landstr1, Sutton SM2 5NG, Surrey, England ; NorthShore Univ HealthSystem, Ctr Med Genet, Evanston, IL 1000 USA;Univ Chicago, Pritzker Sch Med, 924 E 57th St, Chicago, IL 60637 USA ; Harvard TH Chan Sch Publ Hlth, Program Genet Epidemiol & Stat Genet, 677 Huntington Ave, Boston, MA 02115 USA ; BC Canc Agcy, Vancouver Gen Hosp, British Columbias Ovarian Canc Res OVCARE Program, 3427-600 West 10th Ave, Vancouver, BC V5Z 4E6, Canada;Univ British Columbia, 3427-600 West 10th Ave, Vancouver, BC V5Z 4E6, Canada;BC Canc Agcy Res Ctr, Dept Mol Oncol, 3427-600 West 10th Ave, Vancouver, BC V5Z 4E6, Canada ; Univ British Columbia, Dept Pathol & Lab Med, 3427-600 West 10th Ave, Vancouver, BC V5Z 4E6, Canada;NNPetrov Inst Oncol, Leningradskaya Ul 68, St Petersburg 197758, Russia ; Georgetown Univ, Lombardi Comprehens Canc Ctr, 3800 Reservoir Rd, Washington, DC 20007 USA ; Pomeranian Med Univ, Dept Genet & Pathol, Int Hereditary Canc Ctr, ulUnii Lubelskiej 1, PL-71252 Szczecin, Poland;Pomeranian Med Univ, Independent Lab Mol Biol & Genet Diagnost, Rybacka 1, PL-70204 Szczecin, Poland ; Univ Melbourne, Sir Peter MacCallum Dept Oncol, 305 Grattan St, Melbourne, Vic 3000, Australia;Peter MacCallum Canc Ctr, Parkville Familial Canc Ctr, 305 Grattan St, Melbourne, Vic 3000, Australia ; Univ Melbourne, Victorian Comprehens Canc Ctr, Ctr Canc Res, Parkville, Vic 3010, Australia;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Level 1,723 Swanston St, Melbourne, Vic 3010, Australia ; Int Agcy Res Canc, Sect Genet, 150 Cours Albert Thomas, F-69008 Lyon, France ; Umea Univ, Dept Radiat Sci, 6M Van 2, S-90185 Umea, Sweden ; Stanford Univ, Sch Med, Div Oncol, Dept Med, 780 Welch Rd, Stanford, CA 94304 USA;Stanford Univ, Sch Med, Stanford Canc Inst, 780 Welch Rd, Stanford, CA 94304 USA ; Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, 677 Huntington Ave, Boston, MA 02115 USA;Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA 02114 USA ; Med Univ Sofia, Fac Med, Dept Med Chem & Biochem, Mol Med Ctr, Sofia 1504, Bulgaria ; Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Womens Canc Program, 8700 Beverly Blvd, Los Angeles, CA 90048 USA ; Med Univ South Carolina, Hollings Canc Ctr, 68 President St Bioengineering Bldg,MSC955, Charleston, SC 29425 USA;Med Univ South Carolina, Dept Publ Hlth Sci, 68 President St Bioengineering Bldg,MSC955, Charleston, SC 29425 USA ; Univ Med Ctr Hamburg Eppendorf, UCCH, Canc Epidemiol, Martinistr 52, D-20246 Hamburg, Germany ; Univ Cambridge, Dept Publ Hlth & Primary Care, Clin Gerontol, 2 Worts Causeway, Cambridge CB1 8RN, England ; Bashkir State Univ, Dept Genet & Fundamental Med, ulZaki Validi 32, Ufa 450076, Russia;Russian Acad Sci, Inst Biochem & Genet, Ufa Sci Ctr, 71 Prosp Oktyabrya, Ufa 450054, Russia ; Brigham & Womens Hosp, Div Urol Surg, Boston, MA USA ; Radboud Univ Nijmegen, Radboud Inst Hlth Sci, Med Ctr, Geert Grooteplein 21, NL-6525 EZ Nijmegen, Netherlands ; Univ Texas MD Anderson Canc Ctr, Dept Genitourinary Med Oncol, 1155 Pressler St, Houston, TX 77030 USA ; Danish Canc Soc Res Ctr, Dept Virus Lifestyle & Genes, Strandboulevarden 49, DK-2100 Copenhagen, Denmark;Univ Copenhagen, Dept Gynaecol, Rigshosp, Blegdamsvej 9, DK-2100 Copenhagen, Denmark ; Sinai Hlth Syst, Lunenfeld Tanenbaum Res Inst, Prosserman Ctr Populat Hlth Res, 60 Murray St, Toronto, ON M5T 3L9, Canada;Univ Toronto, Dalla Lana Sch Publ Hlth, Div Epidemiol, 155 Coll St, Toronto, ON M5T 3M7, Canada ; Biomed Network Rare Dis CIBERER, AvMonforte Lemos,3-5Pabellon 11Planta 0, Madrid 28029, Spain;ISGlobal, Ctr Res Environm Epidemiol CREAL, Barcelona 08036, Spain;IMIM Hosp del Mar Res Inst, Barcelona 08003, Spain;UPF, Barcelona 08002, Spain ; NCI, Div Canc Epidemiol & Genet, Dept Hlth & Human Serv, NIH, 9609 Med Ctr Dr, Bethesda, MD 20892 USA ; Oslo Univ Hosp, Inst Canc Res, Dept Canc Genet, Radiumhosp, Ullernchausseen 70, N-0379 Oslo, Norway;Univ Oslo, Fac Med, Inst Clin Med, Kirkeveien 166, N-0450 Oslo, Norway;Univ Oslo, Oslo Univ Hosp, Dept Clin Mol Biol, Kirkeveien 166, N-0450 Oslo, Norway ; Maria Sklodowska Curie Inst, Ctr Oncol, Dept Pathol & Lab Diagnost, Roentgena 5, PL-02781 Warsaw, Poland ; Maastricht Univ, Med Ctr, Dept Otorhinolaryngol, Head & Neck Surg, PDebyelaan 25,POBox 5800, NL-6202 AZ Maastricht, Netherlands ; British Columbia Canc Agcy, Dept Integrat Oncol, Room 10-111 675 West 10th Ave, Vancouver, BC V5Z 1L3, Canada ; VIB, VIB Ctr Canc Biol, Herestr 49, B-3001 Leuven, Belgium;Univ Leuven, Dept Human Genet, Lab Translat Genet, Oude Markt 13, B-3000 Leuven, Belgium ; NCI, Integrat Tumor Epidemiol Branch, DCEG, 9609 Med Ctr Dr,Room SG 7E106, Rockville, MD 20850 USA ; Washington State Univ, Coll Pharm, PBS 431 POB 1495, Spokane, WA 99210 USA ; BC Canc Agcy, Canc Control Res, 675 West 10th Ave, Vancouver, BC V5Z 1L3, Canada ; Univ Southern Calif, Keck Sch Med, Dept Prevent Med, 1975 Zonal Ave, Los Angeles, CA 90033 USA ; Carmel Hosp, Clalit Natl Israeli Canc Control Ctr, Clalit Hlth Serv, 2 Horev St, IL-3436212 Haifa, Israel ; Univ Med Ctr Hamburg Eppendorf, Inst Human Genet, Martinistr 52, D-20246 Hamburg, Germany ; Mem Sloan Kettering Canc Ctr, Dept Surg, Gynecol Serv, 1275 York Ave, New York, NY 10065 USA;NYU Langone Med Ctr, Laura & Isaac Pearlmutter Canc Ctr, Gynecol Oncol, 240 East 38th St 19th Floor, New York, NY 10016 USA ; Case Western Reserve Univ, Mary Ann Swetland Ctr Environm Hlth, Dept Family Med & Community Hlth, Cleveland, OH 44106 USA;Inst Invest Sanitaria Santiago de Compostela IDIS, Serv Galego Saude SERGAS, Santiago De Compostela 15706, Spain ; Fred Hutchinson Canc Res Ctr, Translat Res Program, Seattle, WA 98109 USA ; Karolinska Inst, Karolinska Univ Hosp, Dept Mol Med & Surg, S-17176 Stockholm, Sweden ; Mayo Clin Arizona, Hlth Sci Res, 13400 EShea Blvd, Scottsdale, AZ 85259 USA ; Princess Margaret Canc Ctr, Div Epidemiol, 610 Univ Ave, Toronto, ON M5G 2M9, Canada ; Ist Oncol Veneto IRCCS, Dept Clin & Expt Oncol, Unit Oncol 1, I-35122 Padua, Italy ; Oslo Univ Hosp, Dept Med Genet, Kirkeveien 166, N-0450 Oslo, Norway ; Univ Hosp Ulm, Inst Human Genet, Prittwitzstr 43, D-89075 Ulm, Germany ; Univ Eastern Finland, Translat Canc Res Area, Yliopistonranta 1, Kuopio 70210, Finland;Univ Eastern Finland, Inst Clin Med Pathol & Forens Med, KuopioYliopistonranta 1, Kuopio 70210, Finland;Kuopio Univ Hosp, Dept Clin Pathol, Imaging Ctr, Puijonlaaksontie 2, Kuopio 70210, Finland ; Univ Hawaii, Program Epidemiol, Ctr Canc, 701 Ilalo St, Honolulu, HI 96813 USA ; Karolinska Inst, Dept Clin Sci & Educ, Sodersjukhuset, S-17177 Stockholm, Sweden ; Univ Hlth Network, Div Gynecol Oncol, Princess Margaret Hosp, 610 Univ Ave,OPG Wing 6-811, Toronto, ON M5G 2M9, Canada ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;Tech Univ Munich, Div Gynaecol & Obstet, Arcisstr 21, D-80333 Munich, Germany ; German Canc Res Ctr, Div Canc Epidemiol, Neuenheimer Feld 280, D-69120 Heidelberg, Germany;Heidelberg Univ, Fac Med, Neuenheimer Feld 672, D-69120 Heidelberg, Germany ; Roswell Pk Canc Inst, Stat & Data Management Ctr, NRG Oncol, Elm & Carlton St, Buffalo, NY 14263 USA ; Canc Council Victoria, Canc Epidemiol & Intelligence Div, 615 St Kilda Rd, Melbourne, Vic 3004, Australia;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Level 1,723 Swanston St, Melbourne, Vic 3010, Australia ; Magee Womens Res Inst, Canc Res Ctr, Pittsburgh, PA 15213 USA;Hillman Canc Ctr, Pittsburgh, PA 15213 USA;Univ Pittsburgh, Sch Med, Dept Obstet Gynecol & Reprod Sci, Div Gynecol Oncol, 300 Halket St, Pittsburgh, PA 15213 USA ; Veneto Inst Oncol IOV IRCCS, Immunol & Mol Oncol Unit, Via Gattamelata 64, I-35128 Padua, Italy ; Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Bellvitge Biomed Res Inst IDIBELL, Catalan Inst Oncol, Barcelona 08908, Spain;Univ Barcelona, Barcelona 08908, Spain ; Roswell Pk Canc Inst, Div Canc Prevent & Control, Elm & Carlton St, Buffalo, NY 14263 USA ; Univ Manchester, Div Populat Hlth Hlth Serv Res & Primary Care, Oxford Rd, Manchester M13 9PL, Lancs, England;Univ Warwick, Warwick Med Sch, Div Hlth Sci, Coventry CV4 7AL, W Midlands, England ; Univ Toronto, Dept Lab Med & Pathobiol, 1 Kings Coll Circle, Toronto, ON M5S 1A8, Canada;Univ Hlth Network, Lab Med Program, 200 Elizabeth St, Toronto, ON M5G 2C4, Canada ; Univ Penn, Perelman Sch Med, Abramson Canc Ctr, Dept Med, 3400 Civ Ctr Blvd, Philadelphia, PA 19104 USA ; Univ Cambridge, Canc Res UK Cambridge Inst, Li Ka Shing Ctr, Robinson Way, Cambridge CB2 0RE, England;Univ Oxford, John Radcliffe Hosp, Nuffield Dept Surg Sci, Fac Med Sci, Oxford OX1 2JD, England;Univ Cambridge, Addenbrookes Hosp, Dept Oncol, Cambridge CB1 8RN, England ; Univ Bristol, NIHR Bristol Biomed Res Ctr Nutr Theme, Upper Maudlin St, Bristol BS2 8AE, Avon, England ; Beckman Res Inst City Hope, Dept Populat Sci, 1500 E Duarte, Duarte, CA 91010 USA ; Univ Helsinki, Helsinki Univ Hosp, Dept Obstet & Gynecol, Haartmaninkatu 8, FIN-00290 Helsinki, Finland ; Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, 1100 Fairview Ave N, Seattle, WA 98109 USA;Univ Washington, Dept Urol, Seattle, WA 98195 USA ; Copenhagen Univ Hosp, Ctr Genom Med, Rigshosp, Blegdamsvej 9, DK-2100 Copenhagen, Denmark ; Latvian Biomed Res & Study Ctr, Ratsupites Str 1, LV-1067 Riga, Latvia ; Univ Calif San Francisco, Canc Genet & Prevent Program, 1600 Div St, San Francisco, CA 94143 USA ; Mem Sloan Kettering Canc Ctr, Dept Canc Biol & Genet, Clin Genet Res Lab, 1275 York Ave, New York, NY 10065 USA;Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, 1275 York Ave, New York, NY 10065 USA ; Natl Inst Oncol, Dept Mol Genet, Rath Gyorgy u7-9, H-1122 Budapest, Hungary ; Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, 2 Worts Causeway, Cambridge CB1 8RN, England;Univ Cambridge, Dept Clin Neurosci, Cambridge CB2 0QQ, England ; Univ Chicago, Ctr Clin Canc Genet, 5841S Maryland Ave, Chicago, IL 60637 USA ; Univ N Carolina, Gillings Sch Global Publ Hlth, Dept Epidemiol, 135 Dauer Dr, Chapel Hill, NC 27599 USA;UNC Lineberger Comprehens Canc Ctr, 450 West Dr, Chapel Hill, NC 27599 USA ; Univ Surrey, Guildford GU2 7XH, Surrey, England ; HLee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, 12902 Magnolia Dr, Tampa, FL 33612 USA ; UCL, Dept Appl Hlth Res, 1-19 Torrington Pl, London WC1E 6BT, England;Univ Cambridge, Dept Oncol, Strangeways Lab, Ctr Canc Genet Epidemiol, Cambridge CB1 8RN, England ; QIMR Berghofer Med Res Inst, Dept Genet & Computat Biol, 300 Herston Rd, Brisbane, Qld 4006, Australia ; Oregon Hlth & Sci Univ, Dept Obstet & Gynecol, 3181 SW Sam Jackson Pk Rd,L-466, Portland, OR 97239 USA;Oregon Hlth & Sci Univ, Knight Canc Inst, 3181 SW Sam Jackson Pk Rd,L-466, Portland, OR 97239 USA ; Harvard Med Sch, Brigham & Womens Hosp, Channing Div Network Med, Dept Med, 181 Longwood Ave, Boston, MA 02115 USA ; Radboud Univ Nijmegen, Med Ctr, Dept Gastroenterol, Geert Grooteplein Zuid 10,Internal BOBox 433, NL-6525 GA Nijmegen, Netherlands ; Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, 1100 Fairview Ave N, Seattle, WA 98109 USA;Univ Washington, Sch Publ Hlth, Dept Epidemiol, 1959 NE Pacific St, Seattle, WA 98195 USA ; Macedonian Acad Sci & Arts, Res Ctr Genet Engn & Biotechnol Georgi DEfremov, Blvd Krste Petkov Misirkov, Skopje 1000, Macedonia ; Univ Bristol, Bristol Dent Sch, Lower Maudlin St, Bristol BS1 2LY, Avon, England ; Bashkir State Univ, Dept Genet & Fundamental Med, ulZaki Validi 32, Ufa 450076, Russia ; INT, Fdn IRCCS, Dept Res, Unit Mol Bases Genet Risk & Genet Testing, Via Giacomo Venezian 1, I-20133 Milan, Italy ; Decode Genet, Sturlugata 8, IS-101 Reykjavik, Iceland ; Univ NSW Sydney, Sch Womens & Childrens Hlth, Fac Med, 18 High St, Sydney, NSW 2052, Australia;Garvan Inst Med Res, Kinghorn Canc Ctr, 384 Victoria St, Sydney, NSW 2010, Australia ; Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, 1161 21st Ave S D3300, Nashville, TN 37232 USA ; Carmel Hosp, Clalit Natl Canc Control Ctr, 7 Michal St, IL-34362 Haifa, Israel;Technion Fac Med, 7 Michal St, IL-34362 Haifa, Israel ; Univ Pretoria, Dept Genet, Private Bag X323, ZA-0007 Arcadia, South Africa ; Yale Sch Publ Hlth, Dept Chron Dis Epidemiol, 60 Coll St, New Haven, CT 06510 USA ; Salzburg Univ, Dept Mol Biol, Canc Ctr Cluster Salzburg, PLUS, Billrothstr11, A-5020 Salzburg, Austria;DKFZ German Canc Res Ctr, Div Epigen & Canc Risk Factors, Neuenheimer Feld 280, D-69120 Heidelberg, Germany;German Ctr Lung Res DZL, TLRC H, D-69120 Heidelberg, Germany ; Erasmus Univ, Med Ctr, Dept Urol, Wytemaweg 80, NL-3015 CN Rotterdam, Netherlands ; Icahn Sch Med Mt Sinai, Dept Radiat Oncol, 1425 Madison Ave, New York, NY 10029 USA;Icahn Sch Med Mt Sinai, Dept Genet & Genom Sci, 1425 Madison Ave, New York, NY 10029 USA ; Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Program Epidemiol, 1100 Fairview Ave N, Seattle, WA 98109 USA;Univ Washington, Dept Epidemiol, M4 C308,1100 Fairview Ave N, Seattle, WA 98109 USA ; Univ Ghent, Fac Med & Hlth Sci, Basic Med Sci, De Pintelaan 185, B-9000 Ghent, Belgium ; Univ Hosp Heraklion, Hereditary Canc Clin, Iraklion 71110, Greece ; NIEHS, Epidemiol Branch, NIH, 111TWAlexander Dr, Res Triangle Pk, NC 27709 USA ; Kings Coll London, Guys Hosp, Guys Hosp Great Maze Pond, Res Oncol, London SE1 9RT, England ; Univ Turku, Inst Biomed, Turku 20014, Finland;Turku Univ Hosp, Dept Med Genet, Div Lab, Turku 20014, Finland;Univ Tampere, Fac Med & Life Sci, Prostate Canc Res Ctr, Tampere 33014, Finland;Univ Tampere, BioMediTech Inst, Tampere 33014, Finland ; Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Div Mol Pathol, Plesmanlaan 121, NL-1066 CX Amsterdam, Netherlands;Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Div Psychosocial Res & Epidemiol, Plesmanlaan 121, NL-1066 CX Amsterdam, Netherlands ; Univ Southern Calif, Keck Sch Med, Dept Prevent Med, 1450 Biggy St, Los Angeles, CA 90033 USA ; Nanjing Med Univ, Collaborat Innovat Ctr Canc Personalized Med, Jiangsu Key Lab Canc Biomarkers Prevent & Treatme, Dept Epidemiol & Biostat,Sch Publ Hlth, 101 Longmian Ave, Nanjing 211166, Jiangsu, Peoples R China ; H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, 12902 Magnolia Dr MRC CANCONT, Tampa, FL 33612 USA ; Icahn Sch Med Mt Sinai, Dept Populat Hlth Sci & Policy, Dept Genet & Genom Sci, 1425 Madison Ave,2nd Floor, New York, NY 10029 USA ; Med Univ Vienna, Dept OB GYN, Waehringer Guertel 18-20, A-1090 Vienna, Austria;Med Univ Vienna, Ctr Comprehens Canc, Waehringer Guertel 18-20, A-1090 Vienna, Austria ; Univ Utah, Dept Internal Med, Hlth Sci Ctr, 295 Chipeta Way, Salt Lake City, UT 84132 USA ; Aarhus Univ Hosp, Dept Mol Med, DK-8200 Aarhus, Denmark;Aarhus Univ, Dept Clin Med, DK-8200 Aarhus, Denmark ; Monash Univ, Sch Clin Sci, Precis Med, Monash Hlth, 246 Clayton Rd, Clayton, Vic 3168, Australia;Univ Melbourne, Dept Clin Pathol, Cnr Grattan St, Melbourne, Vic 3010, Australia;Royal Parade, Melbourne, Vic 3010, Australia ; Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Med 3, Marchioninistr15, D-81377 Munich, Germany ; Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Level 1,723 Swanston St, Melbourne, Vic 3010, Australia;Curtin Univ, Curtin UWA Ctr Genet Origins Hlth & Dis, 35 Stirling Hwy, Perth, WA 6000, Australia;Univ Western Australia, 35 Stirling Hwy, Perth, WA 6000, Australia ; Univ Gothenburg, Inst Clin Sci, Sahlgrenska Canc Ctr, Dept Obstet & Gynecol, Bla Straket 6, S-41345 Gothenburg, Sweden ; Univ S Florida, Coll Med, Epidemiol Ctr, 3650 Spectrum Blvd,Suite 100, Tampa, FL 33612 USA ; Inst Canc Res, Div Genet & Epidemiol, 15 Cotswold Rd, Sutton SM2 5NG, Surrey, England;Inst Canc Res, Div Breast Canc Res, London SW7 3RP, England ; Sch Med Sao Jose do Rio Preto, Dept Mol Biol, Av Brig Faria Lima 5416 Vila Sao Pedro, BR-15090000 Sao Jose Do Rio Preto, SP, Brazil;Univ Sao Paulo, Inst Biosci, Dept Genet & Evolut Biol, Rua Matao 321, BR-05508090 Sao Paulo, SP, Brazil ; Fred Hutchinson Canc Res Ctr, SWOG Stat Ctr, Seattle, WA 98109 USA ; Univ Oviedo, Fac Med, Campus Cristo S-N, E-33006 Oviedo, Spain;CIBERESP, Campus Cristo S-N, Oviedo 33006, Spain ; NIEHS, Epidemiol Branch, NIH, 111TWAlexander Dr, Res Triangle Pk, NC 27709 USA;NIEHS, Epigenet & Stem Cell Biol Lab, NIH, 111TWAlexander Dr, Res Triangle Pk, NC 27709 USA ; Univ Sheffield, Sch Hlth & Related Res ScHARR, Med Stat Grp, Regent Court,30 Regent St, Sheffield S1 4DA, S Yorkshire, England ; Portuguese Oncol Inst, Dept Genet, Rua DrAntonio Bernardino de Almeida 62, P-4220072 Porto, Portugal;Univ Porto, Biomed Sci Inst ICBAS, RJorge de Viterbo Ferreira 228, P-4050013 Porto, Portugal ; Columbia Univ, Mailman Sch Publ Hlth, Dept Epidemiol, 722 West 168th St, New York, NY 10032 USA ; Brigham & Womens Hosp, Obstet & Gynecol Epidemiol Ctr, 221 Longwood Ave RFB 368, Boston, MA 02115 USA;Harvard THChan Sch Publ Hlth, 221 Longwood Ave RFB 368, Boston, MA 02115 USA ; Odense Univ Hosp, Dept Clin Genet, Sonder Blvd 29, DK-5000 Odense C, Denmark ; Haukeland Hosp, Dept Gynecol & Obstet, N-5021 Bergen, Norway;Univ Bergen, Dept Clin Sci, Ctr Canc Biomarkers CCBIO, N-5021 Bergen, Norway ; McGill Univ, Dept Human Genet & Oncol, Program Canc Genet, 1001 Decarie Blvd, Montreal, PQ H4A 3J1, Canada;Univ Cambridge, Dept Med Genet, Hills Rd, Cambridge CB2 0QQ, England ; Ohio State Univ, Dept Canc Biol & Genet, 460W12th Ave, Columbus, OH 43210 USA ; German Canc Res Ctr, Mol Genet Breast Canc, Neuenheimer Feld 580, D-69120 Heidelberg, Germany;Pontificia Univ Javeriana, Inst Human Genet, Carrera 7 40-90, Bogota, Colombia ; Univ Manchester, NIHR Manchester Biomed Res Ctr, Fac Biol Med & Hlth,Manchester Acad Hlth Sci Ctr, Div Canc Sci,Manchester Canc Res Ctr,Hlth Innovat, Manchester M20 4GJ, Lancs, England ; Univ Oxford, Nuffield Dept Populat Hlth, Canc Epidemiol Unit, Oxford OX3 7LF, England ; Beth Israel Deaconess Med Ctr, Dept Med Oncol, 330 Brookline Ave, Boston, MA 02215 USA ; Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, 677 Huntington Ave, Boston, MA 02115 USA;HLee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, 12902 Magnolia Dr, Tampa, FL 33612 USA ; Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, 1100 Fairview Ave N, Seattle, WA 98109 USA;Univ Utah, Huntsman Canc Inst, 2000 Circle Hope,Rm 4125, Salt Lake City, UT 84112 USA;Univ Utah, Dept Populat Hlth Sci, 2000 Circle Hope,Rm 4125, Salt Lake City, UT 84112 USA ; Int Agcy Res Canc, Genet Epidemiol Grp, 150 Cours Albert Thomas, F-69008 Lyon, France;Univ Alberta, Cross Canc Inst, Dept Oncol, 116 St & 85 Ave, Edmonton, AB T6G 2R3, Canada;Univ Alberta, Cross Canc Inst, Div Radiat Oncol, 116 St & 85 Ave, Edmonton, AB T6G 2R3, Canada ; Univ Hosp Leuven, Dept Obstet & Gynaecol, Div Gynecol Oncol, Herestr 49, B-3000 Leuven, Belgium;Univ Hosp Leuven, Leuven Canc Inst, Herestr 49, B-3000 Leuven, Belgium ; Biomed Network Rare Dis CIBERER, AvMonforte Lemos,3-5Pabellon 11Planta 0, Madrid 28029, Spain;Fdn Publ Galega Med Xenom, Calle Choupana S-N, Santiago De Compostela 15706, Spain;Inst Invest Sanitaria Santiago de Compostela, Calle Choupana S-N, Santiago De Compostela 15706, Spain ; Fdn Publ Galega Med Xenom, Calle Choupana S-N, Santiago De Compostela 15706, Spain;Inst Invest Sanitaria Santiago de Compostela, Calle Choupana S-N, Santiago De Compostela 15706, Spain ; QIMR Berghofer Med Res Inst, Populat Hlth Dept, 300 Herston Rd, Brisbane, Qld 4006, Australia ; NIEHS, Biostat & Computat Biol Branch, NIH, 111TWAlexander Dr, Res Triangle Pk, NC 27709 USA ; Univ N Carolina, Dept Otolaryngol Head & Neck Surg, Chapel Hill, NC 27514 USA ; City Hope Clin Canc Genom Community Res Network, 1500 East Duarte Rd, Duarte, CA 91010 USA ; Univ Manchester, Manchester Acad Hlth Sci Ctr, Christie Hosp NHS Fdn Trust, Div Canc Sci,Manchester Canc Res Ctr, Manchester M13 9PL, Lancs, England ; Fred Hutchinson Canc Res Ctr, 1100 Fairview Ave N, Seattle, WA 98109 USA;Univ Washington, Dept Epidemiol, 1100 Fairview Ave N, Seattle, WA 98109 USA ; Stanford Univ, Dept Hlth Res & Policy Epidemiol, Sch Med, 259 Campus Dr, Stanford, CA 94305 USA;Stanford Univ, Dept Biomed Data Sci, Sch Med, 259 Campus Dr, Stanford, CA 94305 USA ; Ludwig Maximilians Univ Munchen, Inst Med Informat Biometry & Epidemiol, Chair Epidemiol, D-85764 Neuherberg, Germany;Ludwig Maximilians Univ Munchen, Inst Med Informat Biometry & Epidemiol, Chair Epidemiol, Munich, Bavaria, Germany;German Res Ctr Environm Hlth GmbH, Helmholtz Zentrum Munchen, Inst Epidemiol, Ingolstadter Landstr1, D-85764 Neuherberg, Germany;Tech Univ Munich, Inst Med Stat & Epidemiol, D-80333 Munich, Germany ; Univ Oulu, Lab Canc Genet & Tumor Biol, Canc & Translat Med Res Unit, Bioctr Oulu, Aapistie 5A, SF-90220 Oulu, Finland;Northern Finland Lab Ctr Oulu, Lab Canc Genet & Tumor Biol, Aapistie 5A, Oulu 90220, Finland ; Univ Sheffield, Weston Pk Hosp, Acad Unit Clin Oncol, Whitham Rd, Sheffield S10 2SJ, S Yorkshire, England ; Mem Univ Newfoundland, Discipline Genet, St John, NF A1C 5S7, Canada ; Univ Texas MD Anderson Canc Ctr, Div Canc Prevent & Populat Sci, Dept Epidemiol, 1515 Holcombe Blvd, Houston, TX 77030 USA ; Natl Inst Occupat Hlth STAMI, Gydas Vei 8, N-0033 Oslo, Norway ; Univ Pittsburgh, Womens Hosp, Sch Med, 300 Halket St, Pittsburgh, PA 15213 USA ; Broad Inst MIT & Harvard, Program Med & Populat Genet, 75 Ames St, Cambridge, MA 02142 USA;Massachusetts Gen Hosp, Ctr Genom Med, Boston, MA 02114 USA;Massachusetts Gen Hosp, Dept Anasthesia, Boston, MA 02114 USA ; Univ Pittsburgh, Grad Sch Publ Hlth, Human Genet, UPMC Canc Pavil,Suite 4C,Off 467,5150 Ctr Ave, Pittsburgh, PA 15232 USA;UPMC Hillman Canc Ctr, Pittsburgh, PA 15232 USA ; Int Agcy Res Canc, Genet Canc Susceptibil Grp, 150 Cours Albert Thomas, F-69008 Lyon, France ; Univ Washington, Sch Publ Hlth, Dept Epidemiol, 1959 NE Pacific St, Seattle, WA 98195 USA ; Inst Canc Res, Div Genet & Epidemiol, 15 Cotswold Rd, Sutton SM2 5NG, Surrey, England;Inst Canc Res, Oncogenet Team, Downs Rd, Sutton SM2 5NG, Surrey, England;Royal Marsden NHS Fdn Trust, Downs Rd, Sutton SM2 5NG, Surrey, England ; Univ Laval, Res Ctr, Ctr Hosp Univ Quebec, Genom Ctr, 2705 Laurier Blvd, Quebec City, PQ G1V 4G2, Canada ; Univ Cambridge, Dept Oncol, Ctr Canc Genet Epidemiol, 2 Worts Causeway, Cambridge CB1 8RN, England;Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, 2 Worts Causeway, Cambridge CB1 8RN, England ; Harvard TH Chan Sch Publ Hlth, Program Genet Epidemiol & Stat Genet, 677 Huntington Ave, Boston, MA 02115 USA;Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, 677 Huntington Ave, Boston, MA 02115 USA;Broad Inst MIT & Harvard, Program Med & Populat Genet, 75 Ames St, Cambridge, MA 02142 USA ; Univ Calif Los Angeles, UCLA Path & Lab Med, 10833 Le Conte Ave, Los Angeles, CA 19009 USA ; Baylor Coll Med, Inst Clin & Translat Res, Epidemiol Sect, Dept Med, One Baylor Plaza,MS BCM451,Suite 100D, Houston, TX 77030 USA ; Harvard TH Chan Sch Publ Hlth, Program Genet Epidemiol & Stat Genet, 677 Huntington Ave, Boston, MA 02115 USA;Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, 677 Huntington Ave, Boston, MA 02115 USA ; Dartmouth Hitchcock Med Ctr, Dept Neurol, 7927 Rubin Bldg,Room 860,One Med Ctr Dr, Lebanon, NH 3756 USA, 2019

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